Herpesviral G Protein-Coupled Receptors Activate NFAT to Induce Tumor Formation via Inhibiting the SERCA Calcium ATPase

G protein-coupled receptors (GPCRs) constitute the largest family of proteins that transmit signal to regulate an array of fundamental biological processes. Viruses deploy diverse tactics to hijack and harness intracellular signaling events induced by GPCR. Herpesviruses encode multiple GPCR homolog...

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Detalhes bibliográficos
Publicado no:PLoS Pathog
Main Authors: Zhang, Junjie, He, Shanping, Wang, Yi, Brulois, Kevin, Lan, Ke, Jung, Jae U., Feng, Pinghui
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4374719/
https://ncbi.nlm.nih.gov/pubmed/25811856
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1004768
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