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In Silico Screening for Novel Inhibitors of DNA Polymerase III Alpha Subunit of Mycobacterium tuberculosis (MtbDnaE2, H(37)R(v))

Tuberculosis, a pandemic disease is caused by Mycobacterium tuberculosis (Mtb). DNA polymerase III encoded by DnaE2 of Mtb is specifically required for its survival in vivo, and hence can be considered to be a potential drug target. Amino acid sequence analysis of the MtbDnaE2 and its human counterp...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Jadaun, Alka, Sudhakar D, Raja, Subbarao, N., Dixit, Aparna
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4374717/
https://ncbi.nlm.nih.gov/pubmed/25811866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0119760
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