Protease Activity of PprI Facilitates DNA Damage Response: Mn(2+)-Dependence and Substrate Sequence-Specificity of the Proteolytic Reaction

The extremophilic bacterium Deinococcus radiodurans exhibits an extraordinary resistance to ionizing radiation. Previous studies established that a protein named PprI, which exists only in the Deinococcus-Thermus family, acts as a general switch to orchestrate the expression of a number of DNA damag...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Wang, Yunguang, Xu, Qiang, Lu, Huiming, Lin, Lin, Wang, Liangyan, Xu, Hong, Cui, Xianyan, Zhang, Hui, Li, Tingting, Hua, Yuejin
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4374696/
https://ncbi.nlm.nih.gov/pubmed/25811789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0122071
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