Control of Middle Ear Inflammatory and Ion Homeostasis Genes by Transtympanic Glucocorticoid and Mineralocorticoid Treatments

HYPOTHESIS: Transtympanic steroid treatment will induce changes in ion homeostasis and inflammatory gene expression to decrease middle ear inflammation due to bacterial inoculation. BACKGROUND: Otitis media is common, but treatment options are limited to systemic antibiotic therapy or surgical inter...

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Bibliographic Details
Published in:PLoS One
Main Authors: Lighthall, Jessyka G., Kempton, J. Beth, Hausman, Frances, MacArthur, Carol J., Trune, Dennis R.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2015
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4374692/
https://ncbi.nlm.nih.gov/pubmed/25811752
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0119228
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