Frequencies of Gag-restricted T-cell escape “footprints” differ across HIV-1 clades A1 and D chronically infected Ugandans irrespective of host HLA B alleles()

OBJECTIVE(S): We evaluated relationships between critical Gag T-cell escape mutations and concomitant T-cell responses to determine whether HLA-restricted Gag mutations that confer protection, occur at similar rates in a population infected with mixed HIV-1 clades A1 and D viruses. METHODS: Assessme...

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Detalhes bibliográficos
Publicado no:Vaccine
Main Authors: Serwanga, Jennifer, Nakiboneka, Ritah, Mugaba, Susan, Magambo, Brian, Ndembi, Nicaise, Gotch, Frances, Kaleebu, Pontiano
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier Science 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4374673/
https://ncbi.nlm.nih.gov/pubmed/25728323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2015.02.037
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