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Atomic force microscopy reveals age-dependent changes in nanomechanical properties of the extracellular matrix of native human menisci: implications for joint degeneration and osteoarthritis

With aging, the menisci become more susceptible to degeneration due to sustained mechanical stress accompanied by age-related changes in the extracellular matrix (ECM). However, the mechanistic relationship between age-related meniscal degeneration and osteoarthritis (OA) development is not yet full...

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Publicat a:Nanomedicine
Autors principals: Kwok, Jeanie, Grogan, Shawn, Meckes, Brian, Arce, Fernando, Lal, Ratnesh, D’Lima, Darryl
Format: Artigo
Idioma:Inglês
Publicat: 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4374607/
https://ncbi.nlm.nih.gov/pubmed/24972006
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nano.2014.06.010
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