Detecting primitive hematopoietic stem cells in total nucleated and mononuclear cell fractions from umbilical cord blood segments and units

BACKGROUND: Rare hematopoietic stem cell populations are responsible for the transplantation engraftment process. Umbilical cord blood (UCB) is usually processed to the total nucleated cell (TNC), but not to the mononuclear cell (MNC) fraction. TNC counts are used to determine UCB unit storage, rele...

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Detalhes bibliográficos
Publicado no:J Transl Med
Main Authors: Patterson, John, Moore, Cally H, Palser, Emily, Hearn, Jason C, Dumitru, Daniela, Harper, Holli A, Rich, Ivan N
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4374586/
https://ncbi.nlm.nih.gov/pubmed/25784613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-015-0434-z
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