Chronic inhibition of superoxide dismutase produces apoptotic death of spinal neurons.

Mutations in the gene for Cu/Zn superoxide dismutase (SOD1) have been detected in some families with an autosomal dominant form of amyotrophic lateral sclerosis; these mutations appear to reduce the activity of this enzyme. To determine whether decreased SOD activity could contribute to motor neuron...

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Dettagli Bibliografici
Autori principali: Rothstein, J D, Bristol, L A, Hosler, B, Brown, R H, Kuncl, R W
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1994
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC43743/
https://ncbi.nlm.nih.gov/pubmed/7910402
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