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Permanent Uncoupling of Male-specific CYP2C11 Transcription / Translation by Perinatal Glutamate

Perinatal exposure of rats and mice to the typically reported 4mg/g bd wt dose of monosodium glutamate (MSG) results in a complete block in GH secretion as well as obesity, growth retardation and a profound suppression of several cytochrome P450s, including CYP2C11, the predominant male-specific iso...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Toxicol Appl Pharmacol
Hauptverfasser: Banerjee, Sarmistha, Das, Rajat Kumar, Giffear, Kelly A., Shapiro, Bernard H.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4374021/
https://ncbi.nlm.nih.gov/pubmed/25697375
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.taap.2015.02.009
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