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Efficient Inference of Parsimonious Phenomenological Models of Cellular Dynamics Using S-Systems and Alternating Regression

The nonlinearity of dynamics in systems biology makes it hard to infer them from experimental data. Simple linear models are computationally efficient, but cannot incorporate these important nonlinearities. An adaptive method based on the S-system formalism, which is a sensible representation of non...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Daniels, Bryan C., Nemenman, Ilya
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4373916/
https://ncbi.nlm.nih.gov/pubmed/25806510
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0119821
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