Tumor-Associated Macrophages in Glioblastoma Multiforme—A Suitable Target for Somatostatin Receptor-Based Imaging and Therapy?

BACKGROUND: Glioblastoma multiforme (GBM) is the most common primary brain tumor in adults. Tumor-associated macrophages (TAM) have been shown to promote malignant growth and to correlate with poor prognosis. [1,4,7,10-tetraazacyclododecane-NN′,N″,N′″-tetraacetic acid]-d-Phe1,Tyr3-octreotate (DOTATA...

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Udgivet i:PLoS One
Main Authors: Lapa, Constantin, Linsenmann, Thomas, Lückerath, Katharina, Samnick, Samuel, Herrmann, Ken, Stoffer, Carolin, Ernestus, Ralf-Ingo, Buck, Andreas K., Löhr, Mario, Monoranu, Camelia-Maria
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2015
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4373835/
https://ncbi.nlm.nih.gov/pubmed/25807228
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0122269
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