Senescence-like growth arrest induced by hydrogen peroxide in human diploid fibroblast F65 cells.
Human diploid fibroblast cells lose replicative potential after a certain number of population doublings. We use this experimental system to investigate the role of oxidative damage in cellular aging. Treating cells with H2O2 at < 300 microM did not affect the viability of the majority of cells when...
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| Published in: | Proc Natl Acad Sci U S A |
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| Main Authors: | , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
National Academy of Sciences
1994
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC43738/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8183882/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.91.10.4130 |
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