Senescence-like growth arrest induced by hydrogen peroxide in human diploid fibroblast F65 cells.

Human diploid fibroblast cells lose replicative potential after a certain number of population doublings. We use this experimental system to investigate the role of oxidative damage in cellular aging. Treating cells with H2O2 at < 300 microM did not affect the viability of the majority of cells w...

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Bibliographic Details
Main Authors: Chen, Q, Ames, B N
Format: Artigo
Language:Inglês
Published: 1994
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC43738/
https://ncbi.nlm.nih.gov/pubmed/8183882
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