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A reinvestigation of a synthetic peptide (TrPepz) designed to mimic trypsin.

Recently, a 29-residue cyclic peptide was synthesized (TrPepz) that was reported to possess nearly the same catalytic activity and specificity as the pancreatic serine protease, trypsin, for hydrolysis of a small ester substrate, N-tosyl-L-arginine methyl ester (TAME), and small and large peptides [...

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書目詳細資料
發表在:Proc Natl Acad Sci U S A
Principais autores: Wells, J A, Fairbrother, W J, Otlewski, J, Laskowski, M, Burnier, J
格式: Artigo
語言:Inglês
出版: National Academy of Sciences 1994
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在線閱讀:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC43734/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8183880/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.91.10.4110
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