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Oral Methylphenidate Alleviates the Fine Motor Dysfunction Caused by Chronic Postnatal Manganese Exposure in Adult Rats

Developmental manganese (Mn) exposure is associated with motor dysfunction in children and animal models, but little is known about the underlying neurochemical mechanisms or the potential for amelioration by pharmacotherapy. We investigated whether methylphenidate (MPH) alleviates fine motor dysfun...

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Detalhes bibliográficos
Publicado no:Toxicol Sci
Principais autores: Beaudin, Stéphane A., Strupp, Barbara J., Lasley, Stephen M., Fornal, Casimir A., Mandal, Shyamali, Smith, Donald R.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4372668/
https://ncbi.nlm.nih.gov/pubmed/25601986
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfv007
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