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Impact of Nanotopography, Heparin Hydrogel Microstructures, and Encapsulated Fibroblasts on Phenotype of Primary Hepatocytes

[Image: see text] Hepatocytes, the main epithelial cell type in the liver, perform most of the biochemical functions of the liver. Thus, maintenance of a primary hepatocyte phenotype is crucial for investigations of in vitro drug metabolism, toxicity, and development of bioartificial liver construct...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:ACS Appl Mater Interfaces
Hauptverfasser: You, Jungmok, Raghunathan, Vijay Krishna, Son, Kyung Jin, Patel, Dipali, Haque, Amranul, Murphy, Christopher J, Revzin, Alexander
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Chemical Society 2014
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4372509/
https://ncbi.nlm.nih.gov/pubmed/25247391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/am504614e
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