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Sex Differences in the Relationship of IL-6 Signaling to Cancer Cachexia Progression

A devastating aspect of cancer cachexia is severe loss of muscle and fat mass. Though cachexia occurs in both sexes, it is not well-defined in the female. The Apc (Min/+) mouse is genetically predisposed to develop intestinal tumors; circulating IL-6 is a critical regulator of cancer cachexia in the...

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Bibliografiske detaljer
Udgivet i:Biochim Biophys Acta
Main Authors: Hetzler, Kimbell L., Hardee, Justin P., Puppa, Melissa J., Narsale, Aditi A., Sato, Shuichi, Davis, J. Mark, Carson, James A.
Format: Artigo
Sprog:Inglês
Udgivet: 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4372501/
https://ncbi.nlm.nih.gov/pubmed/25555992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbadis.2014.12.015
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