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Btk29A-Mediated Tyrosine Phosphorylation of Armadillo/β-Catenin Promotes Ring Canal Growth in Drosophila Oogenesis

Drosophila Btk29A is the ortholog of mammalian Btk, a Tec family nonreceptor tyrosine kinase whose deficit causes X-linked agammaglobulinemia in humans. The Btk29A(ficP) mutation induces multiple abnormalities in oogenesis, including the growth arrest of ring canals, large intercellular bridges that...

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Publié dans:PLoS One
Auteurs principaux: Hamada-Kawaguchi, Noriko, Nishida, Yasuyoshi, Yamamoto, Daisuke
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2015
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4372500/
https://ncbi.nlm.nih.gov/pubmed/25803041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0121484
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