Gp120/CD4 Blocking Antibodies Are Frequently Elicited in ART-Naïve Chronically HIV-1 Infected Individuals

Antibodies with the ability to block the interaction of HIV-1 envelope glycoprotein (Env) gp120 with CD4, including those overlapping the CD4 binding site (CD4bs antibodies), can protect from infection by HIV-1, and their elicitation may be an interesting goal for any vaccination strategy. To identi...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Carrillo, Jorge, Molinos-Albert, Luis Manuel, de la Concepción, Maria Luisa Rodríguez, Marfil, Silvia, García, Elisabet, Derking, Ronald, Sanders, Rogier W., Clotet, Bonaventura, Blanco, Julià
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4372395/
https://ncbi.nlm.nih.gov/pubmed/25803681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0120648
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