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Assessment of In Vivo and In Vitro Genotoxicity of Glibenclamide in Eukaryotic Cells

Glibenclamide is an oral hypoglycemic drug commonly prescribed for the treatment of type 2 diabetes mellitus, whose anti-tumor activity has been recently described in several human cancer cells. The mutagenic potential of such an antidiabetic drug and its recombinogenic activity in eukaryotic cells...

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Détails bibliographiques
Publié dans:PLoS One
Auteurs principaux: de Sant’Anna, Juliane Rocha, Franco, Claudinéia Conationi da Silva, Mathias, Paulo Cezar de Freitas, de Castro-Prado, Marialba Avezum Alves
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4372363/
https://ncbi.nlm.nih.gov/pubmed/25803314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0120675
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