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Human Antibodies Fix Complement to Inhibit Plasmodium falciparum Invasion of Erythrocytes and Are Associated with Protection against Malaria
Antibodies play major roles in immunity to malaria; however, a limited understanding of mechanisms mediating protection is a major barrier to vaccine development. We have demonstrated that acquired human anti-malarial antibodies promote complement deposition on the merozoite to mediate inhibition of...
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| Yayımlandı: | Immunity |
|---|---|
| Asıl Yazarlar: | , , , , , , , , , , , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Cell Press
2015
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4372259/ https://ncbi.nlm.nih.gov/pubmed/25786180 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2015.02.012 |
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