Targeted Ablation, Silencing, and Activation Establish Glycinergic Dorsal Horn Neurons as Key Components of a Spinal Gate for Pain and Itch

The gate control theory of pain proposes that inhibitory neurons of the spinal dorsal horn exert critical control over the relay of nociceptive signals to higher brain areas. Here we investigated how the glycinergic subpopulation of these neurons contributes to modality-specific pain and itch proces...

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Detalhes bibliográficos
Publicado no:Neuron
Main Authors: Foster, Edmund, Wildner, Hendrik, Tudeau, Laetitia, Haueter, Sabine, Ralvenius, William T., Jegen, Monika, Johannssen, Helge, Hösli, Ladina, Haenraets, Karen, Ghanem, Alexander, Conzelmann, Karl-Klaus, Bösl, Michael, Zeilhofer, Hanns Ulrich
Formato: Artigo
Idioma:Inglês
Publicado em: Cell Press 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4372258/
https://ncbi.nlm.nih.gov/pubmed/25789756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2015.02.028
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