Targeted Ablation, Silencing, and Activation Establish Glycinergic Dorsal Horn Neurons as Key Components of a Spinal Gate for Pain and Itch

The gate control theory of pain proposes that inhibitory neurons of the spinal dorsal horn exert critical control over the relay of nociceptive signals to higher brain areas. Here we investigated how the glycinergic subpopulation of these neurons contributes to modality-specific pain and itch proces...

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Bibliografske podrobnosti
izdano v:Neuron
Main Authors: Foster, Edmund, Wildner, Hendrik, Tudeau, Laetitia, Haueter, Sabine, Ralvenius, William T., Jegen, Monika, Johannssen, Helge, Hösli, Ladina, Haenraets, Karen, Ghanem, Alexander, Conzelmann, Karl-Klaus, Bösl, Michael, Zeilhofer, Hanns Ulrich
Format: Artigo
Jezik:Inglês
Izdano: Cell Press 2015
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4372258/
https://ncbi.nlm.nih.gov/pubmed/25789756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2015.02.028
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