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A far-red emitting probe for unambiguous detection of mobile zinc in acidic vesicles and deep tissue

Imaging mobile zinc in acidic environments remains challenging because most small-molecule optical probes display pH-dependent fluorescence. Here we report a reaction-based sensor that detects mobile zinc unambiguously at low pH. The sensor responds reversibly and with a large dynamic range to exoge...

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Detalhes bibliográficos
Publicado no:Chem Sci
Main Authors: Rivera-Fuentes, Pablo, Wrobel, Alexandra T., Zastrow, Melissa L., Khan, Mustafa, Georgiou, John, Luyben, Thomas T., Roder, John C., Okamoto, Kenichi, Lippard, Stephen J.
Formato: Artigo
Idioma:Inglês
Publicado em: Royal Society of Chemistry 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4372157/
https://ncbi.nlm.nih.gov/pubmed/25815162
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c4sc03388d
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