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Mutant KRAS as a critical determinant of the therapeutic response of colorectal cancer

Mutations in the KRAS oncogene represent one of the most prevalent genetic alterations in colorectal cancer (CRC), the third leading cause of cancer-related death in the US. In addition to their well-characterized function in driving tumor progression, KRAS mutations have been recognized as a critic...

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Detalhes bibliográficos
Publicado no:Genes Dis
Main Authors: Knickelbein, Kyle, Zhang, Lin
Formato: Artigo
Idioma:Inglês
Publicado em: Chongqing Medical University 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4372129/
https://ncbi.nlm.nih.gov/pubmed/25815366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.gendis.2014.10.002
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