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Endocannabinoids are conserved inhibitors of the Hedgehog pathway
Hedgehog ligands control tissue development and homeostasis by alleviating repression of Smoothened, a seven-pass transmembrane protein. The Hedgehog receptor, Patched, is thought to regulate the availability of small lipophilic Smoothened repressors whose identity is unknown. Lipoproteins contain l...
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| Publicado en: | Proc Natl Acad Sci U S A |
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| Autores principales: | , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
National Academy of Sciences
2015
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4371992/ https://ncbi.nlm.nih.gov/pubmed/25733905 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1416463112 |
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