Dramatically reduced spliceosome in Cyanidioschyzon merolae

The human spliceosome is a large ribonucleoprotein complex that catalyzes pre-mRNA splicing. It consists of five snRNAs and more than 200 proteins. Because of this complexity, much work has focused on the Saccharomyces cerevisiae spliceosome, viewed as a highly simplified system with fewer than half...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Stark, Martha R., Dunn, Elizabeth A., Dunn, William S. C., Grisdale, Cameron J., Daniele, Anthony R., Halstead, Matthew R. G., Fast, Naomi M., Rader, Stephen D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2015
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PNAS Plus
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4371933/
https://ncbi.nlm.nih.gov/pubmed/25733880
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1416879112
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