The RNA binding protein FXR1 is a new driver in the 3q26-29 amplicon and predicts poor prognosis in human cancers

Aberrant expression of RNA-binding proteins has profound implications for cellular physiology and the pathogenesis of human diseases such as cancer. We previously identified the Fragile X-Related 1 gene (FXR1) as one amplified candidate driver gene at 3q26-29 in lung squamous cell carcinoma (SCC). F...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Qian, Jun, Hassanein, Mohamed, Hoeksema, Megan D., Harris, Bradford K., Zou, Yong, Chen, Heidi, Lu, Pengcheng, Eisenberg, Rosana, Wang, Jing, Espinosa, Allan, Ji, Xiangming, Harris, Fredrick T., Rahman, S. M. Jamshedur, Massion, Pierre P.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2015
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4371932/
https://ncbi.nlm.nih.gov/pubmed/25733852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1421975112
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