Cation-induced kinetic heterogeneity of the intron–exon recognition in single group II introns

RNA is commonly believed to undergo a number of sequential folding steps before reaching its functional fold, i.e., the global minimum in the free energy landscape. However, there is accumulating evidence that several functional conformations are often in coexistence, corresponding to multiple (loca...

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Publicat a:Proc Natl Acad Sci U S A
Autors principals: Kowerko, Danny, König, Sebastian L. B., Skilandat, Miriam, Kruschel, Daniela, Hadzic, Mélodie C. A. S., Cardo, Lucia, Sigel, Roland K. O.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2015
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4371910/
https://ncbi.nlm.nih.gov/pubmed/25737541
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1322759112
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