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On the road with WRAP53β: guardian of Cajal bodies and genome integrity
The WRAP53 gene encodes both an antisense transcript (WRAP53α) that stabilizes the tumor suppressor p53 and a protein (WRAP53β) involved in maintenance of Cajal bodies, telomere elongation and DNA repair. WRAP53β is one of many proteins containing WD40 domains, known to mediate a variety of cellular...
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| Publicado no: | Front Genet |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4371746/ https://ncbi.nlm.nih.gov/pubmed/25852739 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2015.00091 |
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