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Population pharmacokinetics of ampicillin and sulbactam in patients with community-acquired pneumonia: evaluation of the impact of renal impairment

AIMS: The aims of this study were to develop a population pharmacokinetic (PK) model of ampicillin and sulbactam, to identify patient characteristics influencing the PK, and to explore the relationship between dose regimen and degree of renal impairment with exposure and time above minimum inhibitor...

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Detalhes bibliográficos
Publicado no:Br J Clin Pharmacol
Main Authors: Soto, Elena, Shoji, Satoshi, Muto, Chieko, Tomono, Yoshiro, Marshall, Scott
Formato: Artigo
Idioma:Inglês
Publicado em: BlackWell Publishing Ltd 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4371533/
https://ncbi.nlm.nih.gov/pubmed/24102758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.12232
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