Glucocorticoid receptors in the locus coeruleus mediate sleep disorders caused by repeated corticosterone treatment

Stress induced constant increase of cortisol level may lead to sleep disorder, but the mechanism remains unclear. Here we described a novel model to investigate stress mimicked sleep disorders induced by repetitive administration of corticosterone (CORT). After 7 days treatment of CORT, rats showed...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Wang, Zi-Jun, Zhang, Xue-Qiong, Cui, Xiang-Yu, Cui, Su-Ying, Yu, Bin, Sheng, Zhao-Fu, Li, Sheng-Jie, Cao, Qing, Huang, Yuan-Li, Xu, Ya-Ping, Zhang, Yong-He
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4371174/
https://ncbi.nlm.nih.gov/pubmed/25801728
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep09442
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