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Structure and function of a Clostridium difficile sortase enzyme

Sortase enzymes are responsible for covalent anchoring of specific proteins to the peptidoglycan of the cell wall of gram-positive bacteria. In some gram-positive bacteria (e.g. Staphylococcus aureus), sortases have been found to be essential for pathogenesis and their inhibitors are under developme...

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Bibliografische gegevens
Gepubliceerd in:Sci Rep
Hoofdauteurs: Chambers, Christopher J., Roberts, April K., Shone, Clifford C., Acharya, K. Ravi
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group 2015
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4371152/
https://ncbi.nlm.nih.gov/pubmed/25801974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep09449
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