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Caught in Action: Selecting Peptide Aptamers Against Intrinsically Disordered Proteins in Live Cells

Intrinsically disordered proteins (IDPs) or unstructured segments within proteins play an important role in cellular physiology and pathology. Low cellular concentration, multiple binding partners, frequent post-translational modifications and the presence of multiple conformations make it difficult...

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Detalhes bibliográficos
Publicado no:Sci Rep
Principais autores: Cobbert, Jacqueline D., DeMott, Christopher, Majumder, Subhabrata, Smith, Eric A., Reverdatto, Sergey, Burz, David S., McDonough, Kathleen A., Shekhtman, Alexander
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4371151/
https://ncbi.nlm.nih.gov/pubmed/25801767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep09402
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