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Impact of Physicochemical Environment on the Super Disintegrant Functionality of Cross-Linked Carboxymethyl Sodium Starch: Insight on Formulation Precautions

The aim of this work is to improve the understanding of the physicochemical mechanisms involved in the functionality of cross-linked carboxymethyl sodium starch (CCSS) as a tablet super disintegrant (SD). The behavior and properties of this SD (medium uptake, disintegration times, particle size, and...

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Detalhes bibliográficos
Publicado no:AAPS PharmSciTech
Main Authors: Delalonde, Michèle, Fitouri, Raja, Ruiz, Emilie, Bataille, Bernard, Sharkawi, Tahmer
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4370973/
https://ncbi.nlm.nih.gov/pubmed/25348810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12249-014-0121-z
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