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Hydroxyethyl Starch (HES 130/0.4) Impairs Intestinal Barrier Integrity and Metabolic Function: Findings from a Mouse Model of the Isolated Perfused Small Intestine

BACKGROUND: The application of hydroxyethyl starch (HES) for volume resuscitation is controversially discussed and clinical studies have suggested adverse effects of HES substitution, leading to increased patient mortality. Although, the intestine is of high clinical relevance and plays a crucial ro...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Wong, Yuk Lung, Lautenschläger, Ingmar, Dombrowsky, Heike, Zitta, Karina, Bein, Berthold, Krause, Thorsten, Goldmann, Torsten, Frerichs, Inez, Steinfath, Markus, Weiler, Norbert, Albrecht, Martin
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4370845/
https://ncbi.nlm.nih.gov/pubmed/25799493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0121497
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