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Genome-Wide Association Studies in Dogs and Humans Identify ADAMTS20 as a Risk Variant for Cleft Lip and Palate

Cleft lip with or without cleft palate (CL/P) is the most commonly occurring craniofacial birth defect. We provide insight into the genetic etiology of this birth defect by performing genome-wide association studies in two species: dogs and humans. In the dog, a genome-wide association study of 7 CL...

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書誌詳細
出版年:PLoS Genet
主要な著者: Wolf, Zena T., Brand, Harrison A., Shaffer, John R., Leslie, Elizabeth J., Arzi, Boaz, Willet, Cali E., Cox, Timothy C., McHenry, Toby, Narayan, Nicole, Feingold, Eleanor, Wang, Xioajing, Sliskovic, Saundra, Karmi, Nili, Safra, Noa, Sanchez, Carla, Deleyiannis, Frederic W. B., Murray, Jeffrey C., Wade, Claire M., Marazita, Mary L., Bannasch, Danika L.
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2015
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オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4370697/
https://ncbi.nlm.nih.gov/pubmed/25798845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1005059
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