Pharmacokinetics, safety, and efficacy of APF530 (extended-release granisetron) in patients receiving moderately or highly emetogenic chemotherapy: results of two Phase II trials

BACKGROUND: Despite advances with new therapies, a significant proportion of patients (>30%) suffer delayed-onset chemotherapy-induced nausea and vomiting (CINV) despite use of antiemetics. APF530 is a sustained-release subcutaneous (SC) formulation of granisetron for preventing CINV. APF530 phar...

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發表在:Cancer Manag Res
Main Authors: Gabrail, Nashat, Yanagihara, Ronald, Spaczyński, Marek, Cooper, William, O’Boyle, Erin, Smith, Carrie, Boccia, Ralph
格式: Artigo
語言:Inglês
出版: Dove Medical Press 2015
主題:
Original Research
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4370683/
https://ncbi.nlm.nih.gov/pubmed/25834466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/CMAR.S72626
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