ASM-024, a Piperazinium Compound, Promotes the In Vitro Relaxation of β2-Adrenoreceptor Desensitized Tracheas

Inhaled β2-adrenoreceptor agonists are widely used in asthma and chronic obstructive pulmonary disease (COPD) for bronchoconstriction relief. β2-adrenoreceptor agonists relax airway smooth muscle cells via cyclic adenosine monophosphate (cAMP) mediated pathways. However, prolonged stimulation induce...

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Vydáno v:PLoS One
Hlavní autoři: Israël-Assayag, Evelyne, Beaulieu, Marie-Josée, Cormier, Yvon
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2015
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4370676/
https://ncbi.nlm.nih.gov/pubmed/25799096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0120095
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