Alternative Polyadenylation Allows Differential Negative Feedback of Human miRNA miR-579 on Its Host Gene ZFR

About half of the known miRNA genes are located within protein-coding host genes, and are thus subject to co-transcription. Accumulating data indicate that this coupling may be an intrinsic mechanism to directly regulate the host gene’s expression, constituting a negative feedback loop. Inevitably,...

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Publicat a:PLoS One
Autors principals: Hinske, Ludwig Christian, Galante, Pedro A. F., Limbeck, Elisabeth, Möhnle, Patrick, Parmigiani, Raphael B., Ohno-Machado, Lucila, Camargo, Anamaria A., Kreth, Simone
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2015
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4370670/
https://ncbi.nlm.nih.gov/pubmed/25799583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0121507
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