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Comprehensive Evaluation of microRNA Expression Profiling Reveals the Neural Signaling Specific Cytotoxicity of Superparamagnetic Iron Oxide Nanoparticles (SPIONs) through N-Methyl-D-Aspartate Receptor

Though nanomaterials are considered as drug carriers or imaging reagents targeting the central nervous system their cytotoxicity effect on neuronal cells has not been well studied. In this study, we treated PC12 cells, a model neuronal cell line, with a nanomaterial that is widely accepted for medic...

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Détails bibliographiques
Publié dans:PLoS One
Auteurs principaux: Sun, Bo, Liu, Rui, Ye, Nan, Xiao, Zhong-Dang
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4370573/
https://ncbi.nlm.nih.gov/pubmed/25798908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0121671
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