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A high molecular weight form of somatostatin-28 (1-12)-like immunoreactive substance without somatostatin-14 immunoreactivity in the rat pancreas. Evidence that somatostatin-14 synthesis can occur independently of somatostatin-28.

Synthesis of somatostatin-14 (S-14) could occur through direct enzymatic processing of precursor somatostatin (prosomatostatin) or via sequential breakdown of prosomatostatin leads to somatostatin-28 (S-28) leads to S-14. If direct processing is important, it should theoretically generate S-14 and a...

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Опубликовано в::J Clin Invest
Главный автор: Patel, Y C
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Clinical Investigation 1983
Предметы:
Online-ссылка:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC437054/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6139388/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI111178
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