Activation of antigen-specific suppressor T cells in the presence of cyclosporin requires interactions between T cells of inducer and suppressor lineage.

To probe the mechanism of suppressor T cell generation in man, we have carried out mixed leukocyte reactions (MLR) in the presence of cyclosporin (CsA), a fungal metabolite which prevents the generation of cytotoxic lymphocytes while permitting activation of suppressor cells. After a 12-d MLR in the...

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Vydáno v:	J Clin Invest
Hlavní autoři:	Mohagheghpour, N, Benike, C J, Kansas, G, Bieber, C, Engleman, E G
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	American Society for Clinical Investigation 1983
Témata:	Research Article
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC437050/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6196379/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI111174
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