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Hyperfibrinolysis, physiologic fibrinolysis, and fibrinolysis shutdown: The spectrum of postinjury fibrinolysis and relevance to antifibrinolytic therapy

BACKGROUND: Fibrinolysis is a physiologic process maintaining patency of the microvasculature. Maladaptive overactivation of this essential function (hyperfibrinolysis) is proposed as a pathologic mechanism of trauma-induced coagulopathy. Conversely, the shutdown of fibrinolysis has also been observ...

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Pubblicato in:J Trauma Acute Care Surg
Autori principali: Moore, Hunter B., Moore, Ernest E., Gonzalez, Eduardo, Chapman, Michael P., Chin, Theresa L., Silliman, Christopher C., Banerjee, Anirban, Sauaia, Angela
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4370273/
https://ncbi.nlm.nih.gov/pubmed/25051384
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/TA.0000000000000341
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