The Novel Role of Tyrosine Kinase Inhibitor in the Reversal of Immune Suppression and Modulation of Tumor Microenvironment for Immune-Based Cancer Therapies

In tumor-bearing hosts, myeloid-derived suppressor cells (MDSC) and T regulatory cells (Treg) play important roles in immune suppression, the reversal of which is vitally important for the success of immune therapy. We have shown that ckit ligand is required for MDSC accumulation and Treg developmen...

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Pubblicato in:Cancer Res
Autori principali: Ozao-Choy, Junko, Ma, Ge, Kao, Johnny, Wang, George X., Meseck, Marcia, Sung, Max, Schwartz, Myron, Divino, Celia M., Pan, Ping-Ying, Chen, Shu-Hsia
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4370269/
https://ncbi.nlm.nih.gov/pubmed/19276342
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-08-4709
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