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The Novel Role of Tyrosine Kinase Inhibitor in the Reversal of Immune Suppression and Modulation of Tumor Microenvironment for Immune-Based Cancer Therapies

In tumor-bearing hosts, myeloid-derived suppressor cells (MDSC) and T regulatory cells (Treg) play important roles in immune suppression, the reversal of which is vitally important for the success of immune therapy. We have shown that ckit ligand is required for MDSC accumulation and Treg developmen...

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Vydáno v:Cancer Res
Hlavní autoři: Ozao-Choy, Junko, Ma, Ge, Kao, Johnny, Wang, George X., Meseck, Marcia, Sung, Max, Schwartz, Myron, Divino, Celia M., Pan, Ping-Ying, Chen, Shu-Hsia
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4370269/
https://ncbi.nlm.nih.gov/pubmed/19276342
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-08-4709
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