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Cross-Talk between Human Mast Cells and Bronchial Epithelial Cells in Plasminogen Activator Inhibitor-1 Production via Transforming Growth Factor-β1

Previous reports suggest that plasminogen activator inhibitor-1 (PAI-1) promotes airway remodeling and that human and mouse mast cells (MCs) are an important source of PAI-1. In the present study we investigated MC–epithelial cell (EC) interactions in the production of PAI-1. We stimulated the human...

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Detalhes bibliográficos
Publicado no:Am J Respir Cell Mol Biol
Main Authors: Cho, Seong H., Lee, Sun H., Kato, Atsushi, Takabayashi, Tetsuji, Kulka, Marianna, Shin, Soon C., Schleimer, Robert P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Thoracic Society 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4370249/
https://ncbi.nlm.nih.gov/pubmed/24987792
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2013-0399OC
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