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Generation of three dimensional retinal tissue with functional photoreceptors from human iPSCs

Many forms of blindness result from the dysfunction or loss of retinal photoreceptors. Induced pluripotent stem cells (iPSC) hold great potential for the modeling of these diseases or as potential therapeutic agents. However, to fulfill this promise, a remaining challenge is to induce human iPSC to...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Zhong, Xiufeng, Gutierrez, Christian, Xue, Tian, Hampton, Christopher, Vergara, M. Natalia, Cao, Li-Hui, Peters, Ann, Park, Tea-Soon, Zambidis, Elias T., Meyer, Jason S., Gamm, David M., Yau, King-Wai, Canto-Soler, M. Valeria
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4370190/
https://ncbi.nlm.nih.gov/pubmed/24915161
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms5047
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