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Therapeutic Efficacy and Macrofilaricidal Activity of Doxycycline for the Treatment of River Blindness
Background. Onchocerca volvulus and lymphatic filariae, causing river blindness and elephantiasis, depend on endosymbiotic Wolbachia bacteria for growth, development, fertility, and survival. Clinical trials have shown that doxycycline treatment eliminates Wolbachia, causing long-term sterilization...
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| Publicado no: | Clin Infect Dis |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4370165/ https://ncbi.nlm.nih.gov/pubmed/25537873 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cid/ciu1152 |
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