Langerin-expressing dendritic cells in human tissues are related to CD1c(+) dendritic cells and distinct from Langerhans cells and CD141(high) XCR1(+) dendritic cells

Langerin is a C-type lectin expressed at high level by LCs of the epidermis. Langerin is also expressed by CD8(+)/CD103(+) XCR1(+) cross-presenting DCs of mice but is not found on the homologous human CD141(high) XCR1(+) myeloid DC. Here, we show that langerin is expressed at a low level on DCs isol...

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Bibliographic Details
Published in:J Leukoc Biol
Main Authors: Bigley, Venetia, McGovern, Naomi, Milne, Paul, Dickinson, Rachel, Pagan, Sarah, Cookson, Sharon, Haniffa, Muzlifah, Collin, Matthew
Format: Artigo
Language:Inglês
Published: Society for Leukocyte Biology 2015
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4370053/
https://ncbi.nlm.nih.gov/pubmed/25516751
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.1HI0714-351R
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