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Biochemical and Immunologic Analysis of Hereditary Myeloperoxidase Deficiency

Myeloperoxidase (MPO), a heme enzyme present in the azurophilic granules of human polymorphonuclear neutrophils (PMN), is important in the oxygen-dependent microbicidal activity of PMN. MPO deficiency, defined as the lack of PMN peroxidative activity, is a common genetic defect of human PMN. The pur...

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Detalles Bibliográficos
Main Authors: Nauseef, William M., Root, Richard K., Malech, Harry L.
Formato: Artigo
Idioma:Inglês
Publicado: 1983
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC436991/
https://ncbi.nlm.nih.gov/pubmed/6189859
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