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Isolation and chemical characterization of 2-hydroxybenzoylglycine as a drug binding inhibitor in uremia.
An organic compound that inhibits drug binding in uremia has been isolated from the sera of chronic renal failure patients, and its chemical structure has been determined. Addition of the compound to normal human sera in vitro resulted in drug binding defects similar to those seen in uremia. The pur...
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| Publicado no: | J Clin Invest |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
1983
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC436990/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6853715/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI110879 |
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