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A functional in vitro model of heterotypic interactions reveals a role for interferon-positive carcinoma associated fibroblasts in breast cancer

BACKGROUND: Cancer-associated fibroblasts (CAFs) play an important role in breast cancer pathogenesis by paracrine regulation of breast cancer cell biology. Several in vitro and mouse models have characterized the role of cell contact and cytokine molecules mediating this relationship, although few...

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Detalles Bibliográficos
Publicado en:BMC Cancer
Main Authors: Hosein, Abdel Nasser, Livingstone, Julie, Buchanan, Marguerite, Reid, James F, Hallett, Michael, Basik, Mark
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4369836/
https://ncbi.nlm.nih.gov/pubmed/25884794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-015-1117-0
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